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KMID : 1138520080110020081
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Journal of Pharmacopuncture
2008 Volume.11 No. 2 p.81 ~ p.85
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Eye Irritation Test of Bovis Calculus Pharmacopuncture Solutions for Eye Drop
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Seo Hyeong-Sik
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Abstract
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Objective : This study was done to investigate the safety of Bovis Calculus pharmacopuncture solution manufactured with freezing dryness method to use eye drop.
Methods : The eye irritation test of this material was performed according to the Regulation of Korea Food & Drug Administration (2005. 10. 21, KFDA 2005-60). After Bovis Calculus pharmacopuncture solution was medicated in the left eye of the rabbits, the auther observed eye irritation of the cornea, iris, conjunctiva at 1, 2, 3, 4 & 7day.
Results : 1. After Bovis Calculus pharmacopuncture solution was medicated in the left eye of the rabbits, there wasn’t physical problem at 9 rabbits. 2. After Bovis Calculus pharmacopuncture solutionwas medicated in the left eye of the rabbits, there wasn’t eye irritation of the cornea, iris, conjunctiva at 1, 2, 3, 4 & 7day.
Conclusions : I suggested that Bovis Calculus pharmacopuncture solution didn’t induced eye irritation in rabbits.
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KEYWORD
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Bovis Calculus pharmacopuncture solution, eye irritation test, eye drop
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